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Ligand-targeted cancer therapeutics has been developed to minimize the non-specific cytotoxicity via ligand-drug conjuga......
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Engineered nanogel with superior tissue affinity and cell targeting toward orthotopic bladder cancer
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Presently,the majority of effective chemotherapy agents are administrated by in jection,resulting in reduced patient com......
Nanocarriers delivering prodrugs are important strategies to improve the in vivo effectiveness and efficiency.For therap......
Background: Protein is the material basis of life, it is a major activity executor.Apoptosis proteins play a very import......
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本文对蛋白质中二硫键附近的残基进行了计算机统计分析,结果发现平行和反平行残基间存在着特异的配对规律。这种残基间的相互作用......
基于肿瘤细胞内外还原性环境而设计合成还原敏感型肿瘤靶向药物得到人们的关注。小分子药物在偶联时由于化学结构发生改变,导致药......
